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Selective disruption of PPARγ2 impairs the development of adipose tissue and insulin sensitivity
Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that plays a pivotal role in obesity and diabetes. PPARγ has two isoforms, PPARγ1 and PPARγ2. We investigated the functional differences between PPARγ1 and PPARγ2 by selectively disrupting PPARγ2 in mice. In contrast to the e...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC489998/ https://ncbi.nlm.nih.gov/pubmed/15249658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403652101 |
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