Selective disruption of PPARγ2 impairs the development of adipose tissue and insulin sensitivity

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that plays a pivotal role in obesity and diabetes. PPARγ has two isoforms, PPARγ1 and PPARγ2. We investigated the functional differences between PPARγ1 and PPARγ2 by selectively disrupting PPARγ2 in mice. In contrast to the e...

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Bibliografiske detaljer
Main Authors: Zhang, Jifeng, Fu, Mingui, Cui, Taixing, Xiong, Chen, Xu, Kefeng, Zhong, Wei, Xiao, Yan, Floyd, Donna, Liang, Jian, Li, En, Song, Qing, Chen, Yuqing E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC489998/
https://ncbi.nlm.nih.gov/pubmed/15249658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403652101
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