Disruption of inducible 6-phosphofructo-2-kinase impairs the suppressive effect of PPARγ activation on diet-induced intestine inflammatory response()

PFKFB3is a target gene of peroxisome proliferator-activated receptor gamma (PPARγ) and encodes for inducible 6-phosphofructo-2-kinase (iPFK2). As a key regulatory enzyme that stimulates glycolysis, PFKFB3/iPFK2 links adipocyte metabolic and inflammatory responses. Additionally, PFKFB3/iPFK2 is invol...

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Bibliografiske detaljer
Main Authors: Guo, Xin, Li, Honggui, Xu, Hang, Halim, Vera, Thomas, Laura N., Woo, Shih-Lung, Huo, Yuqing, Chen, Y. Eugene, Sturino, Joseph M., Wu, Chaodong
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584194/
https://ncbi.nlm.nih.gov/pubmed/22841546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2012.04.007
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