IL-15 super-agonist (ALT-803) enhances natural killer (NK) cell function against ovarian cancer

OBJECTIVE: Natural killer (NK) cells represent a powerful immunotherapeutic target as they lyse tumors directly, do not require differentiation, and can elicit potent inflammatory responses. The objective of these studies was to use an IL-15 super-agonist complex, ALT-803 (Altor BioScience Corporati...

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Bibliographic Details
Published in:Gynecol Oncol
Main Authors: Felices, M., Chu, S., Kodal, B., Bendzick, L., Ryan, C., Lenvik, A.J., Boylan, K.L.M., Wong, H.C., Skubitz, A.P.N., Miller, J.S., Geller, M.A.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447472/
https://ncbi.nlm.nih.gov/pubmed/28236454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2017.02.028
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