Potent Cytolytic Activity and Specific IL15 Delivery in a 2(nd) Generation Trispecific Killer Engager

Natural killer (NK) cells are potent immune modulators that can quickly lyse tumor cells and elicit inflammatory responses. These characteristics make them ideal candidates for immunotherapy. However, unlike T cells, NK cells do not possess clonotypic receptors capable of specific antigen recognitio...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Felices, Martin, Lenvik, Todd R., Kodal, Behiye, Lenvik, Alexander J., Hinderlie, Peter, Bendzick, Laura E., Schirm, Dawn K., Kaminski, Michael F., McElmurry, Ron T., Geller, Melissa A., Eckfeldt, Craig E., Vallera, Daniel A., Miller, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484162/
https://ncbi.nlm.nih.gov/pubmed/32661096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0837
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