NK-Cell-Mediated Targeting of Various Solid Tumors Using a B7-H3 Tri-Specific Killer Engager In Vitro and In Vivo

SIMPLE SUMMARY: B7-H3 costimulatory ligand has sparked tremendous interest as a target for antibody-directed therapy of solid tumors. This is attributed to high expression of B7-H3 on the surface of tumor and low expression on normal tissues. Natural killer cells are known as key effectors of the in...

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Библиографические подробности
Опубликовано в: :Cancers (Basel)
Главные авторы: Vallera, Daniel A., Ferrone, Soldano, Kodal, Behiye, Hinderlie, Peter, Bendzick, Laura, Ettestad, Brianna, Hallstrom, Caroline, Zorko, Nicholas A., Rao, Arpit, Fujioka, Naomi, Ryan, Charles J., Geller, Melissa A., Miller, Jeffrey S., Felices, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564091/
https://ncbi.nlm.nih.gov/pubmed/32961861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092659
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