Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death

The endoplasmic reticulum, the cytoplasmic organelle that matures a massive amount of nascent secretory polypeptides, is particularly sensitive to stress. Endoplasmic reticulum stress causes unfolded proteins to populate the organelle, eliciting the unfolded protein response. During the unfolded pro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Pinkaew, Decha, Chattopadhyay, Abhijnan, King, Matthew D., Chunhacha, Preedakorn, Liu, Zhihe, Stevenson, Heather L., Chen, Yanjie, Sinthujaroen, Patuma, McDougal, Owen M., Fujise, Ken
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446404/
https://ncbi.nlm.nih.gov/pubmed/28550308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00029-1
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