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Aneuploidy in Cancer and Aging
Chromosomal instability (CIN), the persistent inability of a cell to faithfully segregate its genome, is a feature of many cancer cells. It stands to reason that CIN enables the acquisition of multiple cancer hallmarks; however, there is a growing body of evidence suggesting that CIN impairs cellula...
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| Publicado no: | Annu Rev Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5445725/ https://ncbi.nlm.nih.gov/pubmed/27893964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-120215-035303 |
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