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Aneuploidy in health, disease, and aging

Aneuploidy, an aberrant number of chromosomes, has been recognized as a feature of human malignancies for over a century, but compelling evidence for causality was largely lacking until mouse models for chromosome number instability were used. These in vivo studies have not only uncovered important...

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Detalhes bibliográficos
Main Authors: Ricke, Robin M., van Deursen, Jan M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613689/
https://ncbi.nlm.nih.gov/pubmed/23547028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301061
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