A carregar...

Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation

High expression of the mitotic kinase Bub1 is associated with a variety of human cancers and correlates with poor clinical prognosis, but whether Bub1 alone can drive tumorigenesis was unknown. We provided conclusive evidence that Bub1 has oncogenic properties by generating transgenic mice that over...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ricke, Robin M, van Deursen, Jan M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266005/
https://ncbi.nlm.nih.gov/pubmed/22033440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.21.18156
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!