Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression

The human growth hormone (hGH) minigene used for transgene stabilization in mice has been recently identified to be locally expressed in the tissues where transgenes are active and associated with phenotypic alterations. Here we extend these findings by analyzing the effect of the hGH minigene in Tg...

全面介紹

Na minha lista:
書目詳細資料
發表在:Sci Rep
Main Authors: Kaklamanos, Aimilios, Rozman, Jan, Roulis, Manolis, Karagianni, Niki, Armaka, Maria, Wu, Moya, Brachthäuser, Laura, Calzada-Wack, Julia, Horsch, Marion, Beckers, Johannes, Rathkolb, Birgit, Adler, Thure, Neff, Frauke, Wolf, Eckhard, Gailus-Durner, Valerie, Fuchs, Helmut, de Angelis, Martin Hrabe, Kollias, George
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445072/
https://ncbi.nlm.nih.gov/pubmed/28546545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02581-8
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍