Uromodulin Retention in Thick Ascending Limb of Henle's Loop Affects SCD1 in Neighboring Proximal Tubule: Renal Transcriptome Studies in Mouse Models of Uromodulin-Associated Kidney Disease

Uromodulin-associated kidney disease (UAKD) is a hereditary progressive renal disease which can lead to renal failure and requires renal replacement therapy. UAKD belongs to the endoplasmic reticulum storage diseases due to maturation defect of mutant uromodulin and its retention in the enlarged end...

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Опубликовано в: :PLoS One
Главные авторы: Horsch, Marion, Beckers, Johannes, Fuchs, Helmut, Gailus-Durner, Valérie, Hrabě de Angelis, Martin, Rathkolb, Birgit, Wolf, Eckhard, Aigner, Bernhard, Kemter, Elisabeth
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237372/
https://ncbi.nlm.nih.gov/pubmed/25409434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113125
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