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Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors

Hepatitis C virus (HCV) strains belong to seven genotypes with numerous subtypes that respond differently to antiviral therapies. Genotype 1, and primarily subtype 1b, is the most prevalent genotype worldwide. The development of recombinant HCV infectious cell culture systems for different variants,...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pham, Long V., Ramirez, Santseharay, Carlsen, Thomas H. R., Li, Yi-Ping, Gottwein, Judith M., Bukh, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444172/
https://ncbi.nlm.nih.gov/pubmed/28348150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00037-17
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