Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors

Hepatitis C virus (HCV) strains belong to seven genotypes with numerous subtypes that respond differently to antiviral therapies. Genotype 1, and primarily subtype 1b, is the most prevalent genotype worldwide. The development of recombinant HCV infectious cell culture systems for different variants,...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Pham, Long V., Ramirez, Santseharay, Carlsen, Thomas H. R., Li, Yi-Ping, Gottwein, Judith M., Bukh, Jens
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444172/
https://ncbi.nlm.nih.gov/pubmed/28348150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00037-17
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