Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors

Hepatitis C virus (HCV) strains belong to seven genotypes with numerous subtypes that respond differently to antiviral therapies. Genotype 1, and primarily subtype 1b, is the most prevalent genotype worldwide. The development of recombinant HCV infectious cell culture systems for different variants,...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Pham, Long V., Ramirez, Santseharay, Carlsen, Thomas H. R., Li, Yi-Ping, Gottwein, Judith M., Bukh, Jens
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2017
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444172/
https://ncbi.nlm.nih.gov/pubmed/28348150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00037-17
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