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Selective up-regulation of PDE1B2 upon monocyte-to-macrophage differentiation

Granulocyte–macrophage colony-stimulating factor (GM-CSF) is a major regulator of monocyte to macrophage differentiation. In both humans and mice, the main phenotype of decreased GM-CSF function is pulmonary proteinosis due to aberrant function of alveolar macrophages. Recently, this cytokine has be...

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Detalhes bibliográficos
Main Authors: Bender, Andrew T., Ostenson, Cari L., Wang, Edith H., Beavo, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544304/
https://ncbi.nlm.nih.gov/pubmed/15625104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408535102
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