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PDE1B2 regulates cGMP and a subset of the phenotypic characteristics acquired upon macrophage differentiation from a monocyte
Monocyte-to-macrophage differentiation with the cytokine granulocyte–macrophage colony-stimulating factor induces expression of the cyclic nucleotide phosphodiesterase PDE1B2. However, what role PDE1B2 plays in macrophage biology has not been elucidated. We have addressed this question by inhibiting...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1326187/ https://ncbi.nlm.nih.gov/pubmed/16407168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509972102 |
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