PDE5 is converted to an activated state upon cGMP binding to the GAF A domain

Lignende værker

• Individual Cerebellar Purkinje Cells Express Different cGMP Phosphodiesterases (PDEs): In Vivo Phosphorylation of cGMP-Specific PDE (PDE5) as an Indicator of cGMP-dependent protein kinase (PKG) Activation
  af: Shimizu-Albergine, Masami, et al.
  Udgivet: (2003)
• Calcium/Calpain mediated regulation of cyclic nucleotide phosphodiesterases, PDE3A and PDE5, in human platelets
  af: Rybalkina, Irina G, et al.
  Udgivet: (2011)
• cGMP kinase I, cardiac hypertrophy and PDE inhibition
  af: Patrucco, Enrico, et al.
  Udgivet: (2011)
• The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding
  af: Martinez, Sergio E., et al.
  Udgivet: (2002)
• Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: INSIGHTS INTO NUCLEOTIDE SPECIFICITY, DIMERIZATION, AND cGMP-DEPENDENT CONFORMATIONAL CHANGE
  af: Heikaus, Clemens C., et al.
  Udgivet: (2008)