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Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophages
Macrophages are central mediators of the innate immune system that can be differentiated from monocytes upon exposure to cytokines. While increased cyclic adenosine monophosphate (cAMP) levels are known to inhibit many lipopolysaccharide-elicited macrophage inflammatory responses, the effects of ele...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799834/ https://ncbi.nlm.nih.gov/pubmed/19959669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911684106 |
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