T cell activation up-regulates cyclic nucleotide phosphodiesterases 8A1 and 7A3

Agents that increase intracellular cAMP inhibit the activation and function of T cells and can lead to cell death. Recently, it has been postulated that cAMP inhibits T cell function in large part by acting as a brake on the T cell receptor and costimulatory receptor pathways. Therefore, for full ac...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Glavas, Natalie A., Ostenson, Cari, Schaefer, Jonathan B., Vasta, Valeria, Beavo, Joseph A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11371644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.101131098
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