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Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

We report here the cloning, expression, and characterization of human PDE11A1, a member of a distinct cyclic nucleotide phosphodiesterase (PDE) family. PDE11A exhibits ≤50% amino acid identity with the catalytic domains of all other PDEs, being most similar to PDE5, and has distinct biochemical prop...

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Detalhes bibliográficos
Main Authors: Fawcett, Lindsay, Baxendale, Rhona, Stacey, Peter, McGrouther, Collette, Harrow, Ian, Soderling, Scott, Hetman, Joanna, Beavo, Joseph A., Phillips, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16303/
https://ncbi.nlm.nih.gov/pubmed/10725373
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