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Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase

Cyclic nucleotide phosphodiesterases (PDEs) regulate intracellular levels of cAMP and cGMP by hydrolyzing them to their corresponding 5′ monophosphates. We report here the cloning and characterization of a novel cAMP-specific PDE from mouse testis. This unique phosphodiesterase contains a catalytic...

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Detalhes bibliográficos
Main Authors: Soderling, S. H., Bayuga, S. J., Beavo, J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21190/
https://ncbi.nlm.nih.gov/pubmed/9671792
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