Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase

Cyclic nucleotide phosphodiesterases (PDEs) regulate intracellular levels of cAMP and cGMP by hydrolyzing them to their corresponding 5′ monophosphates. We report here the cloning and characterization of a novel cAMP-specific PDE from mouse testis. This unique phosphodiesterase contains a catalytic...

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Bibliographic Details
Main Authors: Soderling, S. H., Bayuga, S. J., Beavo, J. A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC21190/
https://ncbi.nlm.nih.gov/pubmed/9671792
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