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Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

We report here the cloning, expression, and characterization of human PDE11A1, a member of a distinct cyclic nucleotide phosphodiesterase (PDE) family. PDE11A exhibits ≤50% amino acid identity with the catalytic domains of all other PDEs, being most similar to PDE5, and has distinct biochemical prop...

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I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Fawcett, Lindsay, Baxendale, Rhona, Stacey, Peter, McGrouther, Collette, Harrow, Ian, Soderling, Scott, Hetman, Joanna, Beavo, Joseph A., Phillips, Stephen C.
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 2000
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Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16303/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10725373/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050585197
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