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Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

We report here the cloning, expression, and characterization of human PDE11A1, a member of a distinct cyclic nucleotide phosphodiesterase (PDE) family. PDE11A exhibits ≤50% amino acid identity with the catalytic domains of all other PDEs, being most similar to PDE5, and has distinct biochemical prop...

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Autori principali: Fawcett, Lindsay, Baxendale, Rhona, Stacey, Peter, McGrouther, Collette, Harrow, Ian, Soderling, Scott, Hetman, Joanna, Beavo, Joseph A., Phillips, Stephen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC16303/
https://ncbi.nlm.nih.gov/pubmed/10725373
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