Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

We report here the cloning, expression, and characterization of human PDE11A1, a member of a distinct cyclic nucleotide phosphodiesterase (PDE) family. PDE11A exhibits ≤50% amino acid identity with the catalytic domains of all other PDEs, being most similar to PDE5, and has distinct biochemical prop...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Fawcett, Lindsay, Baxendale, Rhona, Stacey, Peter, McGrouther, Collette, Harrow, Ian, Soderling, Scott, Hetman, Joanna, Beavo, Joseph A., Phillips, Stephen C.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16303/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10725373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050585197
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