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Herpes Simplex Virus 1 Infection Activates the Endoplasmic Reticulum Resident Kinase PERK and Mediates eIF-2α Dephosphorylation by the γ(1)34.5 Protein

The γ(1)34.5 protein of herpes simplex virus (HSV) plays a crucial role in virus infection. Although the double-stranded RNA-dependent protein kinase (PKR) is activated during HSV infection, the γ(1)34.5 protein inhibits the activity of PKR by mediating dephosphorylation of the translation initiatio...

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Bibliografische gegevens
Hoofdauteurs: Cheng, Guofeng, Feng, Zongdi, He, Bin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC544103/
https://ncbi.nlm.nih.gov/pubmed/15650164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1379-1388.2005
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