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Regulation of herpes simplex virus γ(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5
Myb34.5 is a herpes simplex virus 1 (HSV-1) mutant deleted in the gene for ribonucleotide reductase (ICP6). It also carries a version of γ(1)34.5 (a viral gene product that promotes the dephosphorylation of eIF-2α) that is under control of the E2F-responsive cellular B-myb promoter, rather than of i...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150923/ https://ncbi.nlm.nih.gov/pubmed/11927614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI10623 |
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