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Herpes Simplex Virus 1 Infection Activates the Endoplasmic Reticulum Resident Kinase PERK and Mediates eIF-2α Dephosphorylation by the γ(1)34.5 Protein
The γ(1)34.5 protein of herpes simplex virus (HSV) plays a crucial role in virus infection. Although the double-stranded RNA-dependent protein kinase (PKR) is activated during HSV infection, the γ(1)34.5 protein inhibits the activity of PKR by mediating dephosphorylation of the translation initiatio...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC544103/ https://ncbi.nlm.nih.gov/pubmed/15650164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1379-1388.2005 |
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