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AlaArg Motif in the Carboxyl Terminus of the γ(1)34.5 Protein of Herpes Simplex Virus Type 1 Is Required for the Formation of a High-Molecular-Weight Complex That Dephosphorylates eIF-2α
The γ(1)34.5 protein of herpes simplex virus (HSV) type 1 functions to prevent the shutoff of protein synthesis mediated by the double-stranded-RNA-dependent protein kinase PKR. This is because γ(1)34.5 associates with protein phosphatase 1 (PP1) through its carboxyl terminus, forming a high-molecul...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114858/ https://ncbi.nlm.nih.gov/pubmed/11264356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.3666-3674.2001 |
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