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Sequencing the mouse genome for the oxidatively modified base 8-oxo-7,8-dihydroguanine by OG-Seq

Oxidative damage to the genome can yield the base 8-oxo-7,8-dihydroguanine (OG). In vitro studies suggested OG would preferentially form in 5′-GG-3′ sequence contexts after exposure to reactive oxygen species. Herein, OG locations in the genome were studied by development of “OG-Seq” to sequence OG...

詳細記述

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書誌詳細
出版年:J Am Chem Soc
主要な著者: Ding, Yun, Fleming, Aaron M., Burrows, Cynthia J.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440228/
https://ncbi.nlm.nih.gov/pubmed/28150947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b12604
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