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8-Oxo-7,8-dihydroguanine, friend and foe: Epigenetic-like regulator versus initiator of mutagenesis
A high flux of reactive oxygen species during oxidative stress results in oxidative modification of cellular components including DNA. Oxidative DNA “damage” to the heterocyclic bases is considered deleterious because polymerases may incorrectly read the modifications causing mutations. A prominent...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5548303/ https://ncbi.nlm.nih.gov/pubmed/28629775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.009 |
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