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8-Oxo-7,8-dihydroguanine, friend and foe: Epigenetic-like regulator versus initiator of mutagenesis
A high flux of reactive oxygen species during oxidative stress results in oxidative modification of cellular components including DNA. Oxidative DNA “damage” to the heterocyclic bases is considered deleterious because polymerases may incorrectly read the modifications causing mutations. A prominent...
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| Vydáno v: | DNA Repair (Amst) |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5548303/ https://ncbi.nlm.nih.gov/pubmed/28629775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.009 |
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