Carregant...

8-Oxo-7,8-dihydroguanine in the Context of a Gene Promoter G-Quadruplex Is an On–Off Switch for Transcription

[Image: see text] Interplay between DNA repair of the oxidatively modified base 8-oxo-7,8-dihydroguanine (OG) and transcriptional activation has been documented in mammalian genes. Previously, we synthesized OG into the VEGF potential G-quadruplex sequence (PQS) in the coding strand of a luciferase...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:ACS Chem Biol
Autors principals: Fleming, Aaron M., Zhu, Judy, Ding, Yun, Burrows, Cynthia J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2017
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604463/
https://ncbi.nlm.nih.gov/pubmed/28829124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00636
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!