HIF1α regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia

The standard treatment for Glioblastoma multiforme (GBM) is surgical resection and subsequent radiotherapy and chemotherapy. Surgical resection of GBM is typically restricted because of its invasive growth, which results in residual tumor cells including glioma stem cells (GSCs) and differentiated c...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Pan, Lan, Chuan, Xiong, Shuanglong, Zhao, Xiuwen, Shan, You’an, Hu, Rong, Wan, Wenwu, Yu, Shuangjiang, Liao, Bin, Li, Guangzhi, Wang, Junwei, Zou, Dewei, Chen, Bing, Feng, Hua, Wu, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438632/
https://ncbi.nlm.nih.gov/pubmed/28427209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15888
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