Hyperbaric oxygen promotes not only glioblastoma proliferation but also chemosensitization by inhibiting HIF1α/HIF2α-Sox2

There exists a consensus that combining hyperbaric oxygen (HBO) and chemotherapy promotes chemotherapy sensitivity in GBM cells. However, few studies have explored the mechanism involved. HIF1α and HIF2α are the two main molecules that contribute to GBM malignant progression by inhibiting apoptosis...

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Vydáno v:Cell Death Discov
Hlavní autoři: Wang, Pan, Gong, Sheng, Pan, Jinyu, Wang, Junwei, Zou, Dewei, Xiong, Shuanglong, Zhao, Lu, Yan, Qian, Deng, Yangming, Wu, Nan, Liao, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119469/
https://ncbi.nlm.nih.gov/pubmed/33986256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00486-0
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