Hyperbaric oxygen promotes not only glioblastoma proliferation but also chemosensitization by inhibiting HIF1α/HIF2α-Sox2

There exists a consensus that combining hyperbaric oxygen (HBO) and chemotherapy promotes chemotherapy sensitivity in GBM cells. However, few studies have explored the mechanism involved. HIF1α and HIF2α are the two main molecules that contribute to GBM malignant progression by inhibiting apoptosis...

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Bibliographic Details
Published in:Cell Death Discov
Main Authors: Wang, Pan, Gong, Sheng, Pan, Jinyu, Wang, Junwei, Zou, Dewei, Xiong, Shuanglong, Zhao, Lu, Yan, Qian, Deng, Yangming, Wu, Nan, Liao, Bin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119469/
https://ncbi.nlm.nih.gov/pubmed/33986256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00486-0
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