HIF1α regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia

The standard treatment for Glioblastoma multiforme (GBM) is surgical resection and subsequent radiotherapy and chemotherapy. Surgical resection of GBM is typically restricted because of its invasive growth, which results in residual tumor cells including glioma stem cells (GSCs) and differentiated c...

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Vydáno v:Oncotarget
Hlavní autoři: Wang, Pan, Lan, Chuan, Xiong, Shuanglong, Zhao, Xiuwen, Shan, You’an, Hu, Rong, Wan, Wenwu, Yu, Shuangjiang, Liao, Bin, Li, Guangzhi, Wang, Junwei, Zou, Dewei, Chen, Bing, Feng, Hua, Wu, Nan
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438632/
https://ncbi.nlm.nih.gov/pubmed/28427209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15888
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