MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation.
MyoD is a master regulatory gene for myogenesis. Its product, the MyoD protein, appears to act by binding to muscle-specific enhancer sequences. We show that MyoD binds cooperatively to two sites in the muscle-specific creatine kinase enhancer; this is dramatically reflected in dissociation-rate mea...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1990
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54379/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2377600/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.15.5623 |
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