A cellular factor stimulates the DNA-binding activity of MyoD and E47.
We show that mixing purified MyoD and E47 proteins results in heterodimers that fail to bind DNA, even though MyoD and E47 homodimers can bind DNA efficiently. Addition of cell extracts or a specific fraction from a cell extract enables the heterodimer to bind DNA, but components in this fraction fa...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8393567/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.14.6483 |
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