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MyoD induces growth arrest independent of differentiation in normal and transformed cells.

MyoD is a gene involved in the control of muscle differentiation. We show that MyoD causes growth arrest when expressed in cell lines derived from tumors or transformed by different oncogenes. MyoD-induced growth inhibition was demonstrated by reduction in the efficiency of colony formation and at t...

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Detalles Bibliográficos
Main Authors: Crescenzi, M, Fleming, T P, Lassar, A B, Weintraub, H, Aaronson, S A
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC54972/
https://ncbi.nlm.nih.gov/pubmed/2236052
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