Use of a conditional MyoD transcription factor in studies of MyoD trans-activation and muscle determination.
DNA sequences encoding the hormone-binding domains of several steroid hormone receptors were fused in frame to the MyoD gene. When the gene for this chimeric protein was expressed in NIH 3T3 or 10T1/2 fibroblasts, these cells displayed hormone-dependent induction of myogenesis. Our experiments focus...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47281/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8396258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.8028 |
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