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Use of a conditional MyoD transcription factor in studies of MyoD trans-activation and muscle determination.

DNA sequences encoding the hormone-binding domains of several steroid hormone receptors were fused in frame to the MyoD gene. When the gene for this chimeric protein was expressed in NIH 3T3 or 10T1/2 fibroblasts, these cells displayed hormone-dependent induction of myogenesis. Our experiments focus...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hollenberg, S M, Cheng, P F, Weintraub, H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8396258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.8028
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