A cellular factor stimulates the DNA-binding activity of MyoD and E47.
We show that mixing purified MyoD and E47 proteins results in heterodimers that fail to bind DNA, even though MyoD and E47 homodimers can bind DNA efficiently. Addition of cell extracts or a specific fraction from a cell extract enables the heterodimer to bind DNA, but components in this fraction fa...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8393567/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.14.6483 |
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