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The activity of cGMP-dependent protein kinase Iα is not directly regulated by oxidation-induced disulfide formation at cysteine 43

The type I cGMP-dependent protein kinases (PKGs) are key regulators of smooth muscle tone, cardiac hypertrophy, and other physiological processes. The two isoforms PKGIα and PKGIβ are thought to have unique functions because of their tissue-specific expression, different cGMP affinities, and isoform...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Kalyanaraman, Hema, Zhuang, Shunhui, Pilz, Renate B., Casteel, Darren E.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437233/
https://ncbi.nlm.nih.gov/pubmed/28360102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C117.787358
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