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The activity of cGMP-dependent protein kinase Iα is not directly regulated by oxidation-induced disulfide formation at cysteine 43

The type I cGMP-dependent protein kinases (PKGs) are key regulators of smooth muscle tone, cardiac hypertrophy, and other physiological processes. The two isoforms PKGIα and PKGIβ are thought to have unique functions because of their tissue-specific expression, different cGMP affinities, and isoform...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Kalyanaraman, Hema, Zhuang, Shunhui, Pilz, Renate B., Casteel, Darren E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437233/
https://ncbi.nlm.nih.gov/pubmed/28360102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C117.787358
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