cGMP-DEPENDENT PROTEIN KINASE ANCHORING BY IRAG REGULATES ITS NUCLEAR TRANSLOCATION AND TRANSCRIPTIONAL ACTIVITY

Type I cGMP-dependent protein kinases (PKGs) translocate to the nucleus to regulate gene expression in some, but not all cell types; we hypothesized that nuclear translocation of PKG may be regulated by extra-nuclear anchoring proteins. The inositol 1,4,5-triphosphate (IP(3)) receptor-associated cGM...

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Détails bibliographiques
Auteurs principaux: Casteel, Darren E., Zhang, Tong, Zhuang, Shunhui, Pilz, Renate B.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2477739/
https://ncbi.nlm.nih.gov/pubmed/18450420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.03.009
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