Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation

Myeloperoxidase (MPO) is synthesized by neutrophil and monocyte precursor cells and contributes to host defense by mediating microbial killing. Although several steps in MPO biosynthesis and processing have been elucidated, many questions remained, such as the structure-function relationship of mono...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Grishkovskaya, Irina, Paumann-Page, Martina, Tscheliessnig, Rupert, Stampler, Johanna, Hofbauer, Stefan, Soudi, Monika, Sevcnikar, Benjamin, Oostenbrink, Chris, Furtmüller, Paul G., Djinović-Carugo, Kristina, Nauseef, William M., Obinger, Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2017
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437232/
https://ncbi.nlm.nih.gov/pubmed/28348079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.775031
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