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Induction of cell cycle arrest by increasing GTP-RhoA levels via Taxol-induced microtubule polymerization in renal cell carcinoma

Renal cell carcinoma (RCC) is the most common neoplasm of the kidney in adults, accounting for ~3% of adult malignancies. Understanding the underlying mechanism of RCC tumorigenesis is necessary to improve patient survival. The present study revealed that Taxol-induced microtubule (MT) polymerizatio...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Ren, Yu, Wang, Xue, Lou, Zhongguan, Huang, Shuaishuai, Zhuang, Haihui, Wang, Yuduo, Weng, Guobin, Wang, Ping
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436224/
https://ncbi.nlm.nih.gov/pubmed/28487984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6543
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