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Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA
The cAMP-PKA cascade is a recognized signaling pathway important in inhibition of inflammatory injury events such as endothelial permeability and leucocyte trafficking, and a critical target of regulation is believed to be inhibition of Rho proteins. Here, we hypothesize that PKA directly phosphoryl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584978/ https://ncbi.nlm.nih.gov/pubmed/18768928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00139.2008 |
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