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Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism

The GTP hydrolysis activities of Rho GTPases are stimulated by GTPase-activating proteins (GAPs), which contain a RhoGAP domain equipped with a characteristic arginine finger and an auxiliary asparagine for catalysis. However, the auxiliary asparagine is missing in the RhoGAP domain of Myo9b (Myo9b-...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Mol Biol
Päätekijät: Yi, Fengshuang, Kong, Ruirui, Ren, Jinqi, Zhu, Li, Lou, Jizhong, Wu, Jane Y., Feng, Wei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714546/
https://ncbi.nlm.nih.gov/pubmed/27363609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.06.014
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