تحميل...
Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates
Human GEN1 and yeast Yen1 are endonucleases with the ability to cleave Holliday junctions (HJs), which are proposed intermediates in recombination. In vivo, GEN1 and Yen1 function secondarily to Mus81, which has weak activity on intact HJs. We show that the genetic relationship is reversed in Drosop...
محفوظ في:
| الحاوية / القاعدة: | Nucleic Acids Res |
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| المؤلفون الرئيسيون: | , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Oxford University Press
2017
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435919/ https://ncbi.nlm.nih.gov/pubmed/28369583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx214 |
| الوسوم: |
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