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Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level
Human GEN1 is a cytosolic homologous recombination protein that resolves persisting four-way Holliday junctions (HJ) after the dissolution of the nuclear membrane. GEN1 dimerization has been suggested to play key role in the resolution of the HJ, but the kinetic details of its reaction remained elus...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6393306/ https://ncbi.nlm.nih.gov/pubmed/30590761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1280 |
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