Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level

Human GEN1 is a cytosolic homologous recombination protein that resolves persisting four-way Holliday junctions (HJ) after the dissolution of the nuclear membrane. GEN1 dimerization has been suggested to play key role in the resolution of the HJ, but the kinetic details of its reaction remained elus...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Sobhy, Mohamed A, Bralić, Amer, Raducanu, Vlad-Stefan, Takahashi, Masateru, Tehseen, Muhammad, Rashid, Fahad, Zaher, Manal S, Hamdan, Samir M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Nucleic Acid Enzymes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6393306/
https://ncbi.nlm.nih.gov/pubmed/30590761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1280
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge