Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level

Human GEN1 is a cytosolic homologous recombination protein that resolves persisting four-way Holliday junctions (HJ) after the dissolution of the nuclear membrane. GEN1 dimerization has been suggested to play key role in the resolution of the HJ, but the kinetic details of its reaction remained elus...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Sobhy, Mohamed A, Bralić, Amer, Raducanu, Vlad-Stefan, Takahashi, Masateru, Tehseen, Muhammad, Rashid, Fahad, Zaher, Manal S, Hamdan, Samir M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Nucleic Acid Enzymes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6393306/
https://ncbi.nlm.nih.gov/pubmed/30590761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1280
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia