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Resolution of single and double Holliday junction recombination intermediates by GEN1

Genetic recombination provides an important mechanism for the repair of DNA double-strand breaks. Homologous pairing and strand exchange lead to the formation of DNA intermediates, in which sister chromatids or homologous chromosomes are covalently linked by four-way Holliday junctions (HJs). Depend...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Shah Punatar, Rajvee, Martin, Maria Jose, Wyatt, Haley D. M., Chan, Ying Wai, West, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5255610/
https://ncbi.nlm.nih.gov/pubmed/28049850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619790114
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