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Human Cell Assays for Synthesis-Dependent Strand Annealing and Crossing over During Double-Strand Break Repair

DNA double-strand breaks (DSBs) are one of the most deleterious types of lesions to the genome. Synthesis-dependent strand annealing (SDSA) is thought to be a major pathway of DSB repair, but direct tests of this model have only been conducted in budding yeast and Drosophila. To better understand th...

詳細記述

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書誌詳細
出版年:G3 (Bethesda)
主要な著者: Zapotoczny, Grzegorz, Sekelsky, Jeff
フォーマット: Artigo
言語:Inglês
出版事項: Genetics Society of America 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386867/
https://ncbi.nlm.nih.gov/pubmed/28179392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.037390
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