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Annealing of Complementary DNA Sequences During Double-Strand Break Repair in Drosophila Is Mediated by the Ortholog of SMARCAL1

DNA double-strand breaks (DSBs) pose a serious threat to genomic integrity. If unrepaired, they can lead to chromosome fragmentation and cell death. If repaired incorrectly, they can cause mutations and chromosome rearrangements. DSBs are repaired using end-joining or homology-directed repair strate...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Holsclaw, Julie Korda, Sekelsky, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419489/
https://ncbi.nlm.nih.gov/pubmed/28258182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.200238
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