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Annealing of Complementary DNA Sequences During Double-Strand Break Repair in Drosophila Is Mediated by the Ortholog of SMARCAL1

DNA double-strand breaks (DSBs) pose a serious threat to genomic integrity. If unrepaired, they can lead to chromosome fragmentation and cell death. If repaired incorrectly, they can cause mutations and chromosome rearrangements. DSBs are repaired using end-joining or homology-directed repair strate...

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Publicat a:Genetics
Autors principals: Holsclaw, Julie Korda, Sekelsky, Jeff
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419489/
https://ncbi.nlm.nih.gov/pubmed/28258182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.200238
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